PROM1
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Official Full Name
prominin 1
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Overview
CD133 (also known as Prominin-1 or AC133) is a 120 kD pentaspan glycoprotein with 5 transmembrane domains which localize to cellular protrusions. CD133 was initially described as a surface antigen specific for human hematopoietic stem cells and as a marke -
Synonyms
PROM1; prominin 1; prominin-1; prominin-like 1; antigen AC133 homolog; prominin-like protein 1; Prom; AC133; CD133; Prom-1; Proml1; 4932416E19Rik;
- Recombinant Proteins
- Chromatography Reagents
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Human Cell
- Human cells
- In Vitro Cell Free System
- Mamanlian cells
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Yeast
- C
- His
- Myc
- DDK
- DYKDDDDK
- Fc
- Flag
- GST
- hFc
- His (Fc)
- Avi
- SUMO
- Myc|DDK
- N/A
- N
- mFc
- Involved Pathway
- Protein Function
- Interacting Protein
- PROM1 Related Articles
- PROM1 Related Research Area
PROM1 involved in several pathways and played different roles in them. We selected most pathways PROM1 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with PROM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Transcriptional misregulation in cancer | SPINT1;ELK4;GOLPH3L;PLAU;CEBPE;WT1;Itgam&Itgb2;TCF3;IL2RB |
PROM1 has several biochemical functions, for example, actinin binding, cadherin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PROM1 itself. We selected most functions PROM1 had, and list some proteins which have the same functions with PROM1. You can find most of the proteins on our site.
Function | Related Protein |
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actinin binding | MICALL2;CSRP3;PDLIM5;PKD2;PROM1;RELA;NFKB1;TTN |
cadherin binding | CTNNAL1;CTNNA1;TBC1D2;JUP;Fert2;CTNNA2;OLFM4;CD46;CTNNB1 |
protein binding | LAT2;FEM1C;C11orf67;NANOS3;SLC3A1;SEC22B;TBRG1;RANBP6;LGALS9C |
PROM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PROM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PROM1.
ACTB; Actb; Cdhr1; PLEKHA5
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, PROM1's role is widely studied in various cancers, including brain, breast, colon, and pancreatic cancers.
Various laboratory techniques, such as flow cytometry, immunohistochemistry, and molecular biology assays, are employed to study PROM1 expression and function.
No, PROM1 is also associated with certain eye disorders and is being researched for potential applications in retinal diseases.
Research suggests that it could be a target for treatments aimed at eliminating cancer stem cells and potentially preventing cancer relapse.
The potential impact on normal stem cells and unintended consequences on healthy tissues are areas of concern when targeting PROM1 for therapies.
Customer Reviews (3)
Write a reviewThey can offer detailed characterization data, including purity, stability, and functional assessments, to support researchers' confidence in using the protein in their trials.
Manufacturers can support researchers in developing assays to measure PROM1 protein levels or activity specific to their clinical trial settings.
This may involve guidance in selecting appropriate detection methods, providing assay components, or optimizing protocols for optimal performance and sensitivity.
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