prss1
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  • Official Full Name
  • protease, serine, 1 (trypsin 1)
  • Background
  • This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.
  • Synonyms
  • PRSS1; protease, serine, 1 (trypsin 1); TRY1; trypsin-1; Alpha-trypsin chain 2; Beta-trypsin; Cationic trypsinogen; Serine protease 1; TRY1_HUMAN; Trypsin I; trypsinogen 1; trypsinogen A; digestive zymogen; nonfunctional trypsin 1; TRP1; TRY4; TRYP1
Cat.#:PRSS1-1047HTag:His
Source (Host):NS0Species:Human
Product nameRecombinant Human PRSS1, His-tagged
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Cat.#:PRSS1-273HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRSS1 Protein, His-tagged
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Cat.#:PRSS1-516HTag:His
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human PRSS1 Protein, His-tagged
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Cat.#:PRSS1-5894HTag:Fc/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PRSS1 protein, Fc/His-tagged
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Cat.#:Prss1-3466RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat Prss1, His-tagged
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Cat.#:PRSS1-4737RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PRSS1 Protein
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Cat.#:PRSS1-3635RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PRSS1 Protein, His-tagged
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Cat.#:PRSS1-30745THTag:
Source (Host):Species:Human
Product nameNative Human PRSS1
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Cat.#:PRSS1-2806HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PRSS1 293 Cell Lysate
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Involved Pathway

PRSS1 involved in several pathways and played different roles in them. We selected most pathways PRSS1 participated on our site, such as Neuroactive ligand-receptor interaction, Pancreatic secretion, Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRSS1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Neuroactive ligand-receptor interaction
DRD4B; GRIN3B; TAAR7D; P2RX4B; ADORA1; GRIA2B; PTGER1C; TAAR5; RXFP1; AVPR1A
Pancreatic secretion
CELA3A; PNLIPRP2; RAB27B; CTRB1; ATP2A2; AMY2B; CPB1; CPB2; RAB11A; PRKCG
Protein digestion and absorption
CELA2A; ATP1B4; CPB2; CELA2B; CPA1; PGA4; COL7A1; CELA3A; ATP1A2; SLC7A7
Influenza A
IFIH1; RAF1; FURIN; NUP98; IFNA6; PIK3CG; TNF; IFNA21; XPO1; PIK3R1

Protein Function

PRSS1 has several biochemical functions, for example, metal ion binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRSS1 itself. We selected most functions PRSS1 had, and list some proteins which have the same functions with PRSS1. You can find most of the proteins on our site.
Function
Related Protein
Function metal ion binding
Related Protein CYP27C1; RTCB; ZBTB39; TATDN1; ARHGEF28; TNK2; STEAP4; ANKZF1; PARP12A; TIMM8A2
Function serine-type endopeptidase activity
Related Protein MCPT1; C2; KLK1; ELANE; GZMF; KLKB1; DPP4; Gzmd; TMPRSS4B; C1S

Interacting Protein

PRSS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRSS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRSS1.
GRB2; ALB; PPP2R2B; STK38L