ACTA1A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Zebrafish | ACTA1A-2499Z | Recombinant Zebrafish ACTA1A | Mammalian Cell | His |
|
- Involved Pathway
- Protein Function
- Interacting Protein
ACTA1A involved in several pathways and played different roles in them. We selected most pathways ACTA1A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ACTA1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ACTA1A has several biochemical functions, for example, ATP binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACTA1A itself. We selected most functions ACTA1A had, and list some proteins which have the same functions with ACTA1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | FLAD1;SMC4;FPGS;DDX50;ABCG2A;HSC70;NME7;PFKFB4L;MAP2K2 |
| nucleotide binding | TIAL1;RBM12B1;PRKACAB;SRSF1;ARL3L2;RAB32A;ABCG2D;ABCA9;CLPXA |
ACTA1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACTA1A here. Most of them are supplied by our site. Hope this information will be useful for your research of ACTA1A.
- Q&As
- Reviews
Q&As (17)
Ask a questionAlpha actins serve as a major constituent of the contractile apparatus in muscle tissues.
Alpha actins are predominantly found in muscle tissues.
Actin isoforms, including alpha, beta, and gamma, have various additional roles in processes such as cell shape maintenance, cell division, endocytosis, and cell signaling.
Beta and gamma actins coexist in most cell types as components of the cytoskeleton, whereas alpha actins are primarily found in muscle tissues.
Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
The transgenic zebrafish models expressing mutant forms of ACTA1a help researchers study the molecular defects underlying ACTA1-related nemaline myopathy. By observing the resulting myopathic phenotypes, they gain insights into the disease mechanisms and potential therapeutic targets.
There are variants like acta1a H42Y, M134V and V165M.
It belongs to actin family.
The three main groups of actin isoforms found in vertebrates are alpha, beta, and gamma actins.
ACTA1a is a gene that codes for the skeletal muscle actin protein in zebrafish. It is the equivalent gene to human ACTA1, which is involved in muscle contraction.
ACTA1a plays a crucial role in muscle contraction by forming part of the actin filaments, which are essential for generating the force required for muscle movement.
Beta and gamma actins play a role in processes such as cell migration, organelle movement, and cytoplasmic streaming within cells.
Beta and gamma actins function as mediators of internal cell motility within most cell types.
Heart development and skeletal muscle formation are related to the transcriptional levels of acta1a.
ACTA1a is the predominant actin expressed in fast myofibers.
The fish expressing mutant actins displayed myopathic phenotypes, including delayed hatching from the chorion and variable degrees of curved bodies. They also exhibited muscle weakness, thin bodies, curved tails, reduced motility, actin aggregates, Z-line thickening, and severe myofibrillar disorganization.
It located in cytoplasm and cytoskeleton.
Customer Reviews (5)
Write a reviewThe protein product's prolonged stability provided me with peace of mind, knowing that I could rely on it whenever I needed
The protein product's precision in delivering consistent results across replicates further validated its quality and suitability for my research
I felt confident in using the protein product, knowing that it underwent rigorous safety testing and met the highest industry standards
The protein product's compatibility with commonly used laboratory equipment and techniques simplified its integration into my existing workflow
The protein product's compatibility with diverse experimental techniques ensured its versatility and applicability across different research areas
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