ADRA2DA
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Danio rerio (Zebrafish) (Brachydanio rerio) | RFL35558DF | Recombinant Full Length Danio Rerio Alpha-2Da Adrenergic Receptor(Adra2Da) Protein, His-Tagged | E.coli expression system | His | Full Length (1-408) | |
Zebrafish | ADRA2DA-9715Z | Recombinant Zebrafish ADRA2DA | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
ADRA2DA involved in several pathways and played different roles in them. We selected most pathways ADRA2DA participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADRA2DA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Neuroactive ligand-receptor interaction | CYSLTR2;Gh;GRIA4;P2RX6;CHRNA2;GRIA2A;TAAR8C;F2RL1.2;THRAA |
ADRA2DA has several biochemical functions, for example, G-protein coupled receptor activity, adrenergic receptor activity, alpha2-adrenergic receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADRA2DA itself. We selected most functions ADRA2DA had, and list some proteins which have the same functions with ADRA2DA. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
G-protein coupled receptor activity | OLFR502;TAAR11;FZD9;S1PR5A;TACR1B;OPN1LW2;TAS2R103;DRD2L;CCR9A |
adrenergic receptor activity | ADRB2B;ADRA1BB;ADRA2DB;ADRB2A;ADRA2DA |
alpha2-adrenergic receptor activity | ADRA2B;ADRA2A;ADRA2DA;ADRA2DB;ADRA2C |
signal transducer activity | OLFCQ19;APOL3;VALOPB;GNG13B;GNB3;OPN1MW4;HTR1AA;LGALS1;GMFB |
ADRA2DA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADRA2DA here. Most of them are supplied by our site. Hope this information will be useful for your research of ADRA2DA.
- Q&As
- Reviews
Q&As (17)
Ask a questionThe extent to which ADRA2DA dysfunction can be corrected or reversed will depend on the specific condition and individual factors. While targeted medications and other interventions may help manage symptoms or slow disease progression, complete reversal of ADRA2DA dysfunction may not be possible in some cases.
ADRA2DA is found in various tissues throughout the body, including the brain, cardiovascular system, and kidneys. While the receptor function is broadly similar in these tissues, there may be some differences in the specific downstream effectors and signaling pathways that are activated by ADRA2DA activation, leading to different physiological responses.
Some current limitations in the understanding of ADRA2DA include a lack of knowledge about the precise mechanisms underlying ADRA2DA function and downstream signaling pathways, as well as the role of genetic and environmental factors in modulating receptor function. Additionally, more research is needed to determine the potential clinical applications of targeting ADRA2DA.
Yes, genetic variations in ADRA2DA have been associated with increased risk for certain medical conditions. For example, certain genetic polymorphisms in ADRA2DA have been linked to increased risk for hypertension and depression. However, genetic variations alone are unlikely to be the sole cause of these conditions, and other factors such as environmental and lifestyle factors may also play a role.
Medical conditions that have been associated with ADRA2DA dysfunction or alterations in expression include hypertension, depression, anxiety, ADHD, and substance abuse disorders.
Possible future applications for targeting ADRA2DA include the development of more effective treatments for conditions such as hypertension, mood disorders, and addiction. ADRA2DA-targeted medications could also potentially be used to improve cognitive function, enhance athletic performance, and mitigate the effects of aging.
Treatment options for medical conditions related to ADRA2DA dysfunction may include medications that target the adrenergic system, such as alpha-2 adrenergic receptor agonists or antagonists, as well as psychotherapy and lifestyle modifications. However, treatment will depend on the specific condition and individual needs of the patient.
ADRA2DA dysfunction has been linked to several mental health conditions, including depression, anxiety, and ADHD. Research suggests that alterations in adrenergic function, including changes in ADRA2DA levels and activity, may play a role in the development and progression of these conditions. Targeting ADRA2DA with medication may therefore be a promising treatment approach for individuals with these conditions.
The fight or flight response is a physiological response to stress that involves increased activity in the adrenergic system, including activation of ADRA2DA receptors. Activation of these receptors helps regulate the physiological response to stress, including blood pressure and heart rate. Dysfunction in the adrenergic system, including alterations in ADRA2DA function, may contribute to overactive or dysfunctional stress responses.
Yes, diet and lifestyle factors can modulate ADRA2DA function. For example, exercise has been shown to increase ADRA2DA expression in certain tissues, while stress and poor sleep quality may impair ADRA2DA function. Dietary factors such as caffeine and alcohol may also affect ADRA2DA function.
Yes, ADRA2DA function can affect mood and behavior. The receptor is involved in the regulation of neurotransmitters such as norepinephrine and dopamine, which are important for mood and behavior. Alterations in ADRA2DA function have been implicated in depression, anxiety, and other mood disorders.
ADRA2DA is involved in the regulation of various physiological processes that are implicated in the development and progression of several medical conditions, including hypertension, depression, anxiety, ADHD, and addiction. Alterations in ADRA2DA function or expression may therefore contribute to the development or progression of these conditions.
ADRA2DA dysfunction may be diagnosed through genetic testing or through measurement of receptor expression or function in biological samples. However, diagnosis may also require a comprehensive evaluation of clinical symptoms and risk factors, as well as appropriate medical testing.
While there is limited research on natural supplements or remedies specifically targeting ADRA2DA function, some natural remedies may have indirect effects on the adrenergic system. For example, certain herbal remedies such as ashwagandha, ginseng, and rhodiola have been shown to reduce stress and improve mood, potentially impacting the adrenergic system. However, it is important to discuss the use of natural supplements with a healthcare provider to ensure they are safe and appropriate for individual use.
Yes, medications that target ADRA2DA can have side effects. For example, alpha-2 adrenergic receptor agonists such as clonidine can cause drowsiness, dry mouth, and low blood pressure, while antagonists such as yohimbine can cause anxiety, increased heart rate, and high blood pressure. It is important to discuss the risks and benefits of these medications with a healthcare provider.
Yes, ongoing research continues to explore the role of ADRA2DA in the development and progression of medical conditions such as hypertension, depression, and addiction. Additionally, researchers are exploring the potential use of ADRA2DA-targeted medications for the treatment of these conditions, and the development of more targeted and effective therapies is ongoing.
ADRA2DA dysfunction has been implicated in the development and progression of addiction, particularly to drugs such as opioids and alcohol. Alterations in ADRA2DA expression or function may contribute to changes in the brain's reward system, leading to increased risk for addiction and difficulty quitting.
Customer Reviews (4)
Write a reviewthe technical support provided by the manufacturer has been outstanding, and they have gone above and beyond to answer my questions and address any problems that have arisen.
I am extremely satisfied with the quality of the protein and the level of support provided by the manufacturer, and I am confident that this combination will enable me to achieve my research goals with maximum efficiency and accuracy.
I am pleased to report that the ADRA2DA protein I have received is of exceptional quality and is highly suitable for my experimental needs.
The purity and solubility of the protein are impressive and I am confident that it will perform well in my assays.
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