AMBRA1B
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Zebrafish | AMBRA1B-8476Z | Recombinant Zebrafish AMBRA1B | Mammalian Cell | His |
|
- Involved Pathway
- Protein Function
- Interacting Protein
AMBRA1B involved in several pathways and played different roles in them. We selected most pathways AMBRA1B participated on our site, such as Cellular responses to stress, Macroautophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMBRA1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cellular responses to stress | DPF1;HSPA7;EGLN3;CBX8A;GABARAPL2;WDR45L;ATG9B;ATG4A;KAT5 |
| Macroautophagy | UVRAG;MAP1LC3C;WDR45L;WIPI2;ATG9A;RB1CC1;WDR45;ATG4A;ATG101 |
AMBRA1B has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by AMBRA1B itself. We selected most functions AMBRA1B had, and list some proteins which have the same functions with AMBRA1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
AMBRA1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMBRA1B here. Most of them are supplied by our site. Hope this information will be useful for your research of AMBRA1B.
- Q&As
- Reviews
Q&As (10)
Ask a questionThe expression of AMBRA1B may differ from AMBRA1A in a cell-type or tissue-specific manner, indicating potential functional diversity.
The isoform-specific interactions of AMBRA1B with autophagy-related proteins can have distinct functional consequences, influencing autophagy regulation and cargo recognition.
AMBRA1B may exhibit isoform-specific effects on autophagosome maturation and lysosomal fusion, impacting the efficiency and specificity of cargo degradation.
AMBRA1B may exhibit differences in subcellular localization and dynamics compared to AMBRA1A during autophagy induction, indicating potential distinct roles in autophagosome formation and trafficking.
Manipulation of AMBRA1B expression levels, either through overexpression or knockdown, can modulate cellular autophagy levels and flux, potentially impacting cellular homeostasis.
AMBRA1B may modulate the activity of Beclin 1 and other autophagy initiation factors in a manner that differs from AMBRA1A, contributing to isoform-specific autophagy regulation.
The post-translational modification pattern of AMBRA1B could differ from AMBRA1A, potentially affecting its stability, interaction partners, and overall function in autophagy.
AMBRA1B likely participates in selective autophagy pathways, such as mitophagy or xenophagy, potentially influencing the clearance of specific cellular targets.
Specific cellular or environmental conditions may regulate the alternative splicing and expression of AMBRA1B, leading to isoform-specific regulation of autophagy under certain contexts.
AMBRA1B's interaction with other cellular processes, such as apoptosis or immune responses, may influence the crosstalk between autophagy and these pathways, contributing to cellular fate determination.
Customer Reviews (3)
Write a reviewReduced assay variability in large-scale protein studies.
Minimal assay interference from endogenous inhibitors.
High specificity in target protein localization studies.
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