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CSTF3

Official Full Name

cleavage stimulation factor, 3 pre-RNA, subunit 3, 77kDa
Overview

The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3 end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms

CSTF3; cleavage stimulation factor, 3 pre-RNA, subunit 3, 77kDa; cleavage stimulation factor, 3 pre RNA, subunit 3, 77kD; cleavage stimulation factor subunit 3; CstF 77; CF-1 77 kDa subunit; CSTF 77 kDa subunit; cleavage stimulation factor 77 kDa subunit;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CSTF3-11652H	Recombinant Human CSTF3, GST-tagged	E.coli	GST	1-103a.a.	$319 / 25μg
Human	CSTF3-2044H	Recombinant Human CSTF3 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CSTF3-7222HCL	Recombinant Human CSTF3 293 Cell Lysate	HEK293	Non		Inquiry
Human	CSTF3-2253HF	Recombinant Full Length Human CSTF3 Protein, GST-tagged	In Vitro Cell Free System	GST	103 amino acids	Inquiry
Mouse	Cstf3-2350M	Recombinant Mouse Cstf3 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Rhesus Macaque	CSTF3-1072R	Recombinant Rhesus monkey CSTF3 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	CSTF3-897R-B	Recombinant Rhesus Macaque CSTF3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	CSTF3-897R	Recombinant Rhesus Macaque CSTF3 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Zebrafish	CSTF3-12288Z	Recombinant Zebrafish CSTF3	Mammalian Cell	His		Inquiry
Chicken	CSTF3-1940C	Recombinant Chicken CSTF3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CSTF3 involved in several pathways and played different roles in them. We selected most pathways CSTF3 participated on our site, such as Cleavage of Growing Transcript in the Termination Region, Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSTF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cleavage of Growing Transcript in the Termination Region	LSM10;CSTF2;NUDT21;LSM11;CLP1;CSTF3;ZFP473;PAPOLA;SLBP
Gene Expression	TET2;CCNC;ZNF550;A1CF;QTRT1;KHSRP;ZNF224;PDCD7;SNAPC2
Processing of Capped Intron-Containing Pre-mRNA	CSTF1;ZCRB1;SNRNP35;TTC6;DNAJC8;PTBP1A;PTBP1;NXF1;SLBP
Processing of Capped Intronless Pre-mRNA	NUDT21;SLBP;CSTF2;CSTF3;PAPOLA;CSTF1;ZFP473;LSM10;CLP1
Processing of Intronless Pre-mRNAs	CSTF2;NUDT21;CLP1;CSTF1;PAPOLA;CSTF3
RNA Polymerase II Transcription	CLP1;CCNT2B;LSM11;SRSF11;NELFE;RNPS1;LSM10;SLBP;NUDT21
RNA Polymerase II Transcription Termination	RNPS1;CSTF2;THOC4;CLP1;CSTF1;NUDT21;U2AF2;ZNF473;ZFP473
mRNA 3-end processing	CLP1;SFRS3A;NUDT21;CSTF2;SRSF11;CSTF3

CSTF3 has several biochemical functions, for example, RNA binding, mRNA binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSTF3 itself. We selected most functions CSTF3 had, and list some proteins which have the same functions with CSTF3. You can find most of the proteins on our site.

Function	Related Protein
RNA binding	FAU;EIF4G1A;PPP1R8;IFIT5;CNOT7;PABPN1;ALYREF;RBM8A;SURF6
mRNA binding	C1QBP;SOSTDC1B;ZFP36;PURB;RPS5;ITM2B;RC3H2;SNRNP70;LUC7L2
poly(A) RNA binding	TRMT6;RPUSD3;SF3B14;BUD13;SRPK2;SRSF2;USP10;SFPQ;KTN1
protein binding	ATP10A;C1QTNF3;FAM46D;MPZL1L;VASH1;MSN;PDLIM3;IL2RG;TNFRSF11A

CSTF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSTF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSTF3.

CDK4; VHL; IKBKE; emrR; 15-deoxy-delta(12,14; ssrna_ug; NPM1; SNW1; RNPS1; FIP1L1; Myh9