UBE2J1

Official Full Name

ubiquitin-conjugating enzyme E2, J1
Overview

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq, Jul 2008]
Synonyms

UBE2J1; ubiquitin-conjugating enzyme E2, J1; UBC6; Ubc6p; CGI-76; NCUBE1; HSPC153; HSPC205; NCUBE-1; HSU93243; ubiquitin-conjugating enzyme E2 J1; HSUBC6e; ubiquitin-conjugating enzyme E2, J1, U; non-canonical ubiquitin-conjugating enzyme 1; yeast ubiquitin-conjugating enzyme UBC6 homolog E; ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast);

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell
Sf9 Insect Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	UBE2J1-126H	Recombinant Human UBE2J1, GST-tagged	Sf9 Insect Cell	GST	Inquiry
Human	UBE2J1-572HCL	Recombinant Human UBE2J1 293 Cell Lysate	HEK293	Non	Inquiry
Human	UBE2J1-312H	Recombinant Human UBE2J1 Protein, His-tagged	E.coli	His	Inquiry
Human	UBE2J1-4945H	Recombinant Human UBE2J1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK	Inquiry
Mouse	Ube2j1-6790M	Recombinant Mouse Ube2j1 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK	Inquiry
Zebrafish	UBE2J1-12784Z	Recombinant Zebrafish UBE2J1	Mammalian Cell	His	Inquiry
Chicken	UBE2J1-6327C	Recombinant Chicken UBE2J1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

UBE2J1 involved in several pathways and played different roles in them. We selected most pathways UBE2J1 participated on our site, such as Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum, Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2J1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ubiquitin mediated proteolysis	SIAH1;UBE2NB;BIRC7;SYVN1;UBE2D1;PIAS4A;TRAF6;UBE2J1;ITCHA
Protein processing in endoplasmic reticulum	HSPA2;RRBP1B;EDEM2;ATF6;EIF2AK2;UBE2E2;NSFL1C;ATXN3L;MAPK8
Parkinsons disease	UBB;mt-Atp8;PINK1;NDUFA9;SLC18A2;DRD1A;NDUFC2;NDUFS4;NDUFC2-KCTD14

UBE2J1 has several biochemical functions, for example, ATP binding, ubiquitin conjugating enzyme activity, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2J1 itself. We selected most functions UBE2J1 had, and list some proteins which have the same functions with UBE2J1. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	UBE2D3;TDRD9;PNCK;ACTR3B;ATP2B3B;CAMK1GA;PPP2R4;NSF;SWAP70
ubiquitin conjugating enzyme activity	UBE2G1;UBE2Q1;UBE2Z;UBE2J1;UBE2A;UBE2D3;UBE2Q2;UBE2E3;UBE2D2A
ubiquitin protein ligase activity	RNF139;PDZD4;RNF175;TRIM37;TRIM3;RNF122;FBXW11;TRAF6;MSL2B
ubiquitin protein ligase binding	CUL1A;UBE2O;RNF40;BAG6;TRIB1;PRKACA;WFS1;RB1;TUBB

UBE2J1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2J1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2J1.

Map3k1; PJA2; CREB3; TRIM27; UBA1; BRCA1; BIRC2; q6nr77_human; LRSAM1; SYVN1; RNF2; TOPORS; RNF5