Active Recombinant Human DMP1 protein, His-tagged

• Cat.No.: DMP1-3790H
• Product Overview: Recombinant Human DMP1 protein(Q13316-1)(Met1-Tyr513), fused with His tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Bio-activity: Measured by its ability to bind human CFH in a functional ELISA.
• Molecular Mass: The recombinant human DMP1 consists of 508 amino acids and predictes a molecular mass of 55.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhDMP1 is approximately 53 kDa.
• Protein length: Met1-Tyr513
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 85 % as determined by SDS-PAGE
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: DMP1 dentin matrix acidic phosphoprotein 1 [ Homo sapiens ]
• Official Symbol: DMP1
• Synonyms: DMP1; dentin matrix acidic phosphoprotein 1; dentin matrix acidic phosphoprotein; dentin matrix protein 1; ARHP; ARHR; DMP-1
• Gene ID: 1758
• mRNA Refseq: NM_001079911
• Protein Refseq: NP_001073380
• MIM: 600980
• UniProt ID: Q13316

Reviews

02/01/2022

This commitment to excellence ensures that researchers are provided with the most advanced and reliable tools for their investigations.

12/16/2020

The DMP1 protein offers numerous advantages in trials and research experiments.

11/01/2017

Not only does it provide reliable and consistent results due to its high quality and purity, but it also holds significant value in understanding cellular processes and disease mechanisms.

Q&As

Can DMP1 be a target for drug development?

Yes, targeting DMP1 in drug development may offer new avenues for treating conditions related to bone and dentin abnormalities.

Are there therapeutic applications of DMP1 in bone-related conditions?

Research suggests that DMP1 may have therapeutic potential in promoting bone regeneration and treating conditions like osteoporosis.

How does DMP1 contribute to the repair of bone fractures?

DMP1 is involved in the repair and remodeling of bone tissue after fractures by influencing the mineralization and structural integrity of the newly formed bone.

How can DMP1 be utilized in diagnostic procedures?

DMP1 levels can be measured in biological samples, such as blood or saliva, to assess the potential presence of dental or skeletal disorders and to monitor disease progression.

Is there a connection between DMP1 and periodontal disease?

Some studies suggest that DMP1 may play a role in maintaining the health of periodontal tissues, and alterations in its expression could be associated with periodontal disease.