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Active Recombinant Human RNASE1, His-tagged

Cat.No. : RNASE1-8588H
Product Overview : Recombinant Human RNASE1 (P07998) (Met1-Thr156), fused with a polyhistidine tag at the C-terminus, was produced in Human Cell.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4
Bio-activity : Measured by its ability to hydrolyze yeast RNA. One unit of the enzyme causes an increase in absorbance of 1.0 at 260 nm in 15 min when yeast RNA is hydrolyzed at 37°C and pH 7.0. The specific activity is >2.5×106 unit/mg.
Molecular Mass : The recombinant human RNASE1 comprises 139 amino acids and has a predicted molecular mass of 16 kDa. The apparent molecular mass of the protein is approximately 29 ,26 and 22 kDa in SDS-PAGE under reducing conditions
Protein Length : Met1-Thr156
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 95 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : RNASE1 ribonuclease, RNase A family, 1 (pancreatic) [ Homo sapiens ]
Official Symbol : RNASE1
Synonyms : RNASE1; ribonuclease, RNase A family, 1 (pancreatic); RNS1; ribonuclease pancreatic; RIB-1; RNase 1; RNase A; HP-RNase; RNase upI-1; ribonuclease 1; ribonuclease A; RIB1; MGC12408;
Gene ID : 6035
mRNA Refseq : NM_002933
Protein Refseq : NP_002924
MIM : 180440
UniProt ID : P07998

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is there an association between RNASE1 protein and insulin secretion? 11/12/2019

There is a correlation between RNASE1 protein and insulin secretion. Studies have shown that RNASE1 protein can regulate insulin synthesis and secretion by affecting the internal environment of pancreatic islets.

Is there a regulatory mechanism for RNASE1 proteins? 10/23/2019

At present, the regulatory mechanism of RNASE1 protein is poorly understood. However, studies have found that some factors such as glucagon and insulin may be involved in regulating the expression and activity of RNASE1 protein.

Does RNASE1 protein have anti-tumor effects? 07/30/2019

The RNASE1 protein is thought to have potential for anti-tumor effects. Studies have shown that it can induce apoptosis of tumor cells and inhibit the proliferation and invasion ability of tumor cells.

What are the applications of RNASE1 protein in clinical diagnosis? 07/15/2019

RNASE1 protein has certain application potential in clinical diagnosis. Its hydrolyzed RNA properties can be used to measure the content and stability of RNA, and then evaluate the condition and treatment effect of certain diseases.

What role does RNASE1 protein play in RNA degradation? 04/23/2019

The RNASE1 protein participates in the RNA degradation process in the digestive system by cutting the phosphodiester bond of the RNA molecule and degrading it into shorter RNA fragments.

Is RNASE1 protein also expressed in the gut? 01/19/2019

The main expression and secretion site of RNASE1 protein is the pancreas, while the expression in the gut is relatively low. But in some cases, other nucleases in the gut may perform a similar function.

Customer Reviews (3)

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Reviews
10/27/2022

    RNASE1 have strong anti-contamination ability and are not easily contaminated, which ensures the quality of the product.

    07/06/2021

      This stability of RNASE1 is impressive, maintaining stable performance regardless of the environment, demonstrating excellent quality and reliability.

      01/08/2020

        The catalytic activity of RNASE1 is excellent, which can simplify complex chemical reactions and improve yields, and has high scientific research value.

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