Active Recombinant Human RNASE1 Protein, His-tagged
Cat.No. : | RNASE1-12H |
Product Overview : | Recombinant human RNASE1 (29-156aa), fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Liquid |
Bio-activity : | Specific activity is > 3 X 10^6 unit/mg, and is defined as the amount of enzyme that hydrolyze 1.0 nmole of RNA per minute at 25 centigrade. |
Molecular Mass : | 15.3 kDa |
Identity : | 134aa |
AA Sequence : | KESRAKKFQRQHMDSDSSPSSSSTY CNQMMRRRNMTQGRCKPVNTFVHEP LVDVQNVCFQEKVTCKNGQGNCYKS NSSMHITDCRLTNGSRYPNCAYRTS PKERHIIVACEGSPYVPVHFDASVE DST |
N-terminal Sequence Analysis : | Lys-Glu-Ser-Arg-Ala |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | 90% by SDS-PAGE |
Applications : | SDS-PAGE, Enzyme Activity |
Storage : | Can be stored at 2 to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/mL (determined by Absorbance at 280nm) |
Storage Buffer : | In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name : | RNASE1 ribonuclease A family member 1, pancreatic [ Homo sapiens (human) ] |
Official Symbol : | RNASE1 |
Synonyms : | RNASE1; ribonuclease A family member 1, pancreatic; RAC1; RIB1; RNS1; ribonuclease pancreatic; HP-RNase; RIB-1; RNase 1; RNase A; RNase upI-1; ribonuclease 1; ribonuclease A C1; ribonuclease, RNase A family, 1 (pancreatic); EC 4.6.1.18 |
Gene ID : | 6035 |
mRNA Refseq : | NM_198235 |
Protein Refseq : | NP_937878 |
MIM : | 180440 |
UniProt ID : | P07998 |
Products Types
◆ Recombinant Protein | ||
RNASE1-1344H | Recombinant Human RNASE1 Protein, MYC/DDK-tagged | +Inquiry |
RNASE1-1893H | Recombinant Human RNASE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Rnase1-5533M | Recombinant Mouse Rnase1 Protein, Myc/DDK-tagged | +Inquiry |
RNASE1-3726R | Recombinant Rhesus Macaque RNASE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Rnase1-396R | Recombinant Rat Rnase1 Protein, His/GST-tagged | +Inquiry |
◆ Lysates | ||
RNASE1-1283HCL | Recombinant Human RNASE1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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