Recombinant Full Length Human CSF1 Protein, GST-tagged
Cat.No. : | CSF1-2156HF |
Product Overview : | Human CSF1 full-length ORF ( NP_000748.3, 1 a.a. - 554 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 86.5 kDa |
Protein length : | 554 amino acids |
AA Sequence : | MTAPGAAGRCPPTTWLGSLLLLVCL LASRSITEEVSEYCSHMIGSGHLQS LQRLIDSQMETSCQITFEFVDQEQL KDPVCYLKKAFLLVQDIMEDTMRFR DNTPNAIAIVQLQELSLRLKSCFTK DYEEHDKACVRTFYETPLQLLEKVK NVFNETKNLLDKDWNIFSKNCNNSF AECSSQDVVTKPDCNCLYPKAIPSS DPASVSPHQPLAPSMAPVAGLTWED SEGTEGSSLLPGEQPLHTVDPGSAK QRPPRSTCQSFEPPETPVVKDSTIG GSPQPRPSVGAFNPGMEDILDSAMG TNWVPEEASGEASEIPVPQGTELSP SRPGGGSMQTEPARPSNFLSASSPL PASAKGQQPADVTGTALPRVGPVRP TGQDWNHTPQKTDHPSALLRDPPEP GSPRISSLRPQGLSNPSTLSAQPQL SRSHSSGSVLPLGELEGRRSTRDRR SPAEPEGGPASEGAARPLPRFNSVP LTDTGHERQSEGSSSPQLQESVFHL LVPSVILVLLAVGGLLFYRWRRRSH QEPQRADSPLEQPEGSPLTQDDRQV ELPV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CSF1 colony stimulating factor 1 (macrophage) [ Homo sapiens ] |
Official Symbol : | CSF1 |
Synonyms : | CSF1; colony stimulating factor 1 (macrophage); macrophage colony-stimulating factor 1; M CSF; MCSF; MGC31930; lanimostim; CSF-1 |
Gene ID : | 1435 |
mRNA Refseq : | NM_000757 |
Protein Refseq : | NP_000748 |
MIM : | 120420 |
UniProt ID : | P09603 |
Products Types
◆ Recombinant Protein | ||
CSF1-40H | Active Recombinant Human CSF1 Protein | +Inquiry |
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CSF1-083C | Active Recombinant Human CSF1 Protein (1-149 aa) | +Inquiry |
Csf1-041M | Active Recombinant Mouse Csf1 Protein | +Inquiry |
Csf1-043M | Recombinant Mouse Csf1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CSF1-1934HCL | Recombinant Human CSF1 cell lysate | +Inquiry |
CSF1-001MCL | Recombinant Mouse CSF1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThe CSF1 protein is renowned for its exceptional quality and reliability, making it an ideal choice to fulfill my experimental requirements.
With its high purity and stability, this protein ensures dependable and accurate results, which are crucial for the success of my research endeavors.
Whether it is for investigating cellular pathways, studying protein functions, or exploring signaling cascades, the CSF1 protein offers unparalleled versatility and performance.
Q&As (5)
Ask a questionCSF1 is implicated in tumor-associated macrophages, influencing tumor growth, invasion, and the tumor microenvironment.
Side effects may include immune-related adverse events, inflammation, and alterations in white blood cell counts.
Yes, there is ongoing research on combining CSF1-targeted therapies with other immunotherapies or conventional treatments to enhance efficacy.
Challenges include maintaining the balance of immune responses, potential off-target effects, and variability in patient responses.
Studies are exploring its role in neuroinflammation, neuroprotection, and potential therapeutic interventions for conditions like Alzheimer's disease.
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