Recombinant Human COL3A1 Protein (Gln24-Pro153), N-His tagged

• Cat.No.: COL3A1-4013H
• Product Overview: Recombinant human PIIINP / COL3A1 (Gln24-Pro153) fused with the N-His tag was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 15.55 kDa
• Protein length: Gln24-Pro153
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02% NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: COL3A1 collagen, type III, alpha 1 [ Homo sapiens (human) ]
• Official Symbol: COL3A1
• Synonyms: COL3A1; collagen, type III, alpha 1; EDS4A, Ehlers Danlos syndrome type IV, autosomal dominant; collagen alpha-1 (III) chain; collagen, fetal; alpha1 (III) collagen; Ehlers-Danlos syndrome type IV, autosomal dominant; EDS4A; FLJ34534
• Gene ID: 1281
• mRNA Refseq: NM_000090
• Protein Refseq: NP_000081
• MIM: 120180
• UniProt ID: P02461

Reviews

01/23/2020

This protein demonstrates great performance in WB assays, providing accurate and reliable results that are crucial for protein analysis.

05/08/2019

The COL3A1 protein is of exceptional quality, making it an ideal choice to meet my experimental needs.

07/27/2016

the COL3A1 protein has proven to be an invaluable tool in protein electron microscopy (EM) structure analysis.

Q&As

How can the study of COL3A1 protein aid in the development of personalized medicine for vEDS patients?

Understanding the specific genetic and protein alterations in vEDS patients can help tailor individualized treatment strategies based on the patient's unique molecular profile.

Can COL3A1 protein analysis be used for prenatal screening of vEDS?

Yes, analysis of COL3A1 protein levels in prenatal samples may provide valuable information for assessing the risk of vEDS in the developing fetus.

How can the measurement of COL3A1 protein levels aid in the early detection of vEDS?

Elevated or decreased levels of COL3A1 protein may serve as potential biomarkers for early detection and risk assessment of vEDS, especially in at-risk individuals or families.

What are the current challenges in the clinical application of COL3A1 protein analysis?

Challenges include the need for standardized assays and reference ranges for COL3A1 protein levels, as well as the interpretation of results in the context of individual patient variability.

Can the measurement of COL3A1 protein levels be used to monitor disease progression in vEDS patients?

Yes, monitoring changes in COL3A1 protein levels may provide insights into disease progression and response to treatment in vEDS patients.