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A2M

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Official Full Name
alpha-2-macroglobulin
Background
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008]
Synonyms
A2M; alpha-2-macroglobulin; A2MD; CPAMD5; FWP007; S863-7; alpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5;
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A2M Related Articles
>> Lee, JH; Cho, CH; et al. Semi-quantitative Measurement of a Specific Glycoform Using a DNA-tagged Antibody and Lectin Affinity Chromatography for Glyco-biomarker Development. MOLECULAR & CELLULAR PROTEOMICS 14:782-795(2015).
>> Vissers, LELM; Bonetti, M; et al. Heterozygous germline mutations in A2ML1 are associated with a disorder clinically related to Noonan syndrome. EUROPEAN JOURNAL OF HUMAN GENETICS 23:317-324(2015).

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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