Recombinant Human A2M Protein, GST-tagged
Cat.No. : | A2M-003H |
Product Overview : | Human A2M partial ORF ( NP_000005.2, 641 a.a. - 730 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 35.64 kDa |
AA Sequence : | DCINRHNVYINGITYTPVSSTNEKD MYSFLEDMGLKAFTNSKIRKPKMCP QLQQYEMHGPEGLRVGFYESDVMGR GHARLVHVEEPHTET |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | A2M alpha-2-macroglobulin [ Homo sapiens ] |
Official Symbol : | A2M |
Synonyms : | A2M; alpha-2-macroglobulin; CPAMD5; FWP007; S863 7; alpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; A2MD; S863-7; DKFZp779B086; |
Gene ID : | 2 |
mRNA Refseq : | NM_000014 |
Protein Refseq : | NP_000005 |
MIM : | 103950 |
UniProt ID : | P01023 |
Products Types
◆ Native Protein | ||
A2m-367M | Native Mouse Alpha-2-Macroglobulin | +Inquiry |
A2m-695R | Native Rat Alpha-2-Macroglobulin | +Inquiry |
◆ Lysates | ||
A2M-593HCL | Recombinant Human A2M cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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