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DKK1

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Official Full Name
dickkopf WNT signaling pathway inhibitor 1
Background
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008]
Synonyms
DKK1; dickkopf WNT signaling pathway inhibitor 1; SK; DKK-1; dickkopf-related protein 1; hDkk-1; dickkopf-1 like; dickkopf 1 homolog; dickkopf-like protein 1; dickkopf related protein-1;
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DKK1 Related Articles
>> Jin, HT; Wang, BL; et al. Anti-DKK1 antibody promotes bone fracture healing through activation of beta-catenin signaling. BONE 71:63-75(2015).
>> Gerbaix, M; Vico, L; et al. Periostin expression contributes to cortical bone loss during unloading. BONE 71:94-100(2015).

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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