Recombinant Human DKK1 Protein, THR32-HIS266, Tag Free, Biotinylated

• Cat.No.: DKK1-068H
• Product Overview: Recombinant human Dickkopf-1 (DKK1) protein was developed from HEK293.

Specification

• Description: This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines.
• Source: HEK293
• Species: Human
• Tag: Tag Free
• Protein length: THR32-HIS266
• Conjugation/Label: Biotin
• Form: Lyophilised
• Endotoxin: Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg).
• Applications: ELISA, WB
• Notes: FOR RESEARCH USE ONLY (RUO).
• Storage: Recombinant DKK1 can be stored in working aliquots at 2 to 8 centigrade for one month, or at -20 to -70 centigrade for 1 year. Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilised from 0.2 μm filtered PBS solution, pH 7.2, 5% Trehalose.

Gene Information

• Gene Name: DKK1 dickkopf 1 homolog (Xenopus laevis) [ Homo sapiens (human) ]
• Official Symbol: DKK1
• Synonyms: DKK1; dickkopf 1 homolog (Xenopus laevis); dickkopf (Xenopus laevis) homolog 1; dickkopf-related protein 1; DKK 1; SK; hDkk-1; dickkopf-1 like; dickkopf related protein-1; DKK-1
• Gene ID: 22943
• mRNA Refseq: NM_012242
• Protein Refseq: NP_036374
• MIM: 605189
• UniProt ID: O94907