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   Your Position: Home >> TREM2

TREM2

Official Full Name

TREM2 triggering receptor expressed on myeloid cells 2

Background

The protein encoded by this gene is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded;protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines.;Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy;(PLOSL).

Synonyms

Trem2a; Trem2b; Trem2c