Recombinant Human TREM2 protein, His-Avi-tagged
Cat.No. : | TREM2-092H |
Product Overview : | Human Trem2 Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains His19-Ser174. |
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Description : | TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta protein 42, a cleavage product of the amyloid-beta precursor protein APP, and mediates its uptake and degradation by microglia. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Molecular Mass : | The protein has a predicted MW of 20.3 kDa. Due to glycosylation, the protein migrates to 30- 38KDa based on Bis-Tris PAGE result. |
Protein length : | His19-Ser174 |
Endotoxin : | Less than 0.2 EU per ug by the LAL method. |
Purity : | > 95% as determined by Bis-Tris PAGE |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Gene Name : | TREM2 triggering receptor expressed on myeloid cells 2 [ Homo sapiens (human) ] |
Official Symbol : | TREM2 |
Synonyms : | PLOSL2; TREM2; TREM-2; Trem2a; Trem2b; Trem2c; TREM-2triggering receptor expressed on myeloid cells 2a; Triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2 |
Gene ID : | 54209 |
mRNA Refseq : | NM_001271821.2 |
Protein Refseq : | NP_001258750.1 |
MIM : | 605086 |
UniProt ID : | Q9NZC2 |
Products Types
◆ Recombinant Protein | ||
Trem2-9578M | Recombinant Mouse Trem2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Trem2-535M | Recombinant Mouse Trem2 Protein, His/GST-tagged | +Inquiry |
TREM2-310H | Active Recombinant Human TREM2 protein(Met1-Ser174), His&Avi-tagged, Biotinylated | +Inquiry |
TREM2-04H | Recombinant Human TREM2 Protein (19-174aa), C-His-tagged | +Inquiry |
TREM2-486H | Recombinant Human TREM2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
TREM2-2186MCL | Recombinant Mouse TREM2 cell lysate | +Inquiry |
TREM2-2649HCL | Recombinant Human TREM2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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