Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email:


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Official Full Name
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
AFP; alpha-fetoprotein; FETA; HPAFP; alpha-fetoglobulin; alpha-1-fetoprotein;
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AFP Related Articles
>> Li, L; Xia, LR; et al. New method for fabricating an alpha-fetoprotein affinity monolithic polymer array. JOURNAL OF APPLIED POLYMER SCIENCE 132:-(2015).
>> Liu, YJ; Li, JS; et al. Theranostic Polymeric Micelles for the Diagnosis and Treatment of Hepatocellular Carcinoma. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 11:613-622(2015).

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127

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