Native Human AFP Protein

• Cat.No.: AFP-412H
• Product Overview: Human AFP native protein from human urine, Iodination Grade.

Specification

• Description: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
• Source: Human
• Species: Human
• Form: Liquid
• Purity: >= 98% by SDS-PAGE
• Applications: Antibody Production
  SDS-PAGE
  Conjugation
• Notes: Universal Precautions. Safe laboratory practices should be used when handling this material.
• Storage: Store at 4centigrade on dry atmosphere or store at -20centigrade for long term storage.After reconstitution, store at -20centigrade.Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: In 0.1M sodium phosphate buffer, 0.2M NaCl, pH 7.4 (0.09% sodium azide)

Gene Information

• Gene Name: AFP alpha-fetoprotein [ Homo sapiens ]
• Official Symbol: AFP
• Synonyms: AFP; alpha-fetoprotein; HPAFP; FETA; alpha-fetoglobulin; alpha-1-fetoprotein
• Gene ID: 174
• mRNA Refseq: NM_001134
• Protein Refseq: NP_001125
• MIM: 104150
• UniProt ID: P02771