Recombinant Human SUMF1 Protein, His (Fc)-Avi-tagged

• Cat.No.: SUMF1-2139H
• Product Overview: Recombinant Human SUMF1 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Human
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: SUMF1 sulfatase modifying factor 1 [ Homo sapiens (human) ]
• Official Symbol: SUMF1
• Synonyms: FGE; UNQ3037; AAPA3037
• Gene ID: 285362
• mRNA Refseq: NM_182760.4
• Protein Refseq: NP_877437.2
• MIM: 607939
• UniProt ID: Q8NBK3

Reviews

02/10/2022

Expert protein engineering support, an invaluable resource for our project.

06/14/2019

Consistent western blot results, a lab necessity for our research.

05/17/2019

Great protein crystallization service, vital for our structural biology work.

Q&As

What is the impact of SUMF1 on lysosomal function and storage diseases?

SUMF1 plays a role in lysosomal function, with implications for lysosomal storage diseases.

How does SUMF1 influence bone development and skeletal disorders?

SUMF1 influences bone growth and development, potentially affecting skeletal health and disorders.

What role does SUMF1 play in the degradation of glycosaminoglycans and mucopolysaccharides?

SUMF1 aids in the degradation of glycosaminoglycans, crucial for the breakdown of these complex molecules.

What are the mechanisms by which SUMF1 modulates cellular detoxification processes?

SUMF1 contributes to cellular detoxification, aiding in the breakdown of potentially harmful substances.

How do alterations in SUMF1 expression or function affect neurological development and function?

Variations in SUMF1 activity can impact neurological development and function, influencing brain health and disease.

How does SUMF1 deficiency contribute to the development of multiple sulfatase deficiency (MSD) and related symptoms?

SUMF1 deficiency leads to multiple sulfatase deficiency, disrupting normal metabolism and causing various symptoms.

How does SUMF1 (Sulfatase Modifying Factor 1) activate sulfatase enzymes involved in cellular metabolism?

SUMF1 is essential for the activation of sulfatase enzymes, impacting their role in cellular metabolism.