Recombinant Human SUMF1 Protein (Ser34-Asp374), C-His tagged

• Cat.No.: SUMF1-5827H
• Product Overview: Recombinant human SUMF1 (Ser34-Asp374) fused with the C-terminal His tag was expressed in mammalian cells.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: C-His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 37.51 kDa
• Protein Length: Ser34-Asp374
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: SUMF1 sulfatase modifying factor 1 [ Homo sapiens (human) ]
• Official Symbol: SUMF1
• Synonyms: SUMF1; sulfatase modifying factor 1; sulfatase-modifying factor 1; FGE; UNQ3037; FGly-generating enzyme; C-alpha-formylglycine-generating enzyme 1; AAPA3037; MGC131853; MGC150436
• Gene ID: 285362
• mRNA Refseq: NM_001164674
• Protein Refseq: NP_001158146
• MIM: 607939
• UniProt ID: Q8NBK3

Reviews

02/10/2022

Expert protein engineering support, an invaluable resource for our project.

06/14/2019

Consistent western blot results, a lab necessity for our research.

05/17/2019

Great protein crystallization service, vital for our structural biology work.

Q&As

What is the impact of SUMF1 on lysosomal function and storage diseases?

SUMF1 plays a role in lysosomal function, with implications for lysosomal storage diseases.

How does SUMF1 influence bone development and skeletal disorders?

SUMF1 influences bone growth and development, potentially affecting skeletal health and disorders.

What role does SUMF1 play in the degradation of glycosaminoglycans and mucopolysaccharides?

SUMF1 aids in the degradation of glycosaminoglycans, crucial for the breakdown of these complex molecules.

What are the mechanisms by which SUMF1 modulates cellular detoxification processes?

SUMF1 contributes to cellular detoxification, aiding in the breakdown of potentially harmful substances.

How do alterations in SUMF1 expression or function affect neurological development and function?

Variations in SUMF1 activity can impact neurological development and function, influencing brain health and disease.

How does SUMF1 deficiency contribute to the development of multiple sulfatase deficiency (MSD) and related symptoms?

SUMF1 deficiency leads to multiple sulfatase deficiency, disrupting normal metabolism and causing various symptoms.

How does SUMF1 (Sulfatase Modifying Factor 1) activate sulfatase enzymes involved in cellular metabolism?

SUMF1 is essential for the activation of sulfatase enzymes, impacting their role in cellular metabolism.