EZH2 is a histone methyltransferase that exhibits methylation activity toward H3-K27.
The EZH2-EED Binding Assay Kit is designed to measure the inhibition of the protein-protein interaction between EZH2 and EED. The key to this kit is the specific binding of EZH2 to EED. With this kit, only two simple steps on a microtiter plate are required. First, incubate a sample containing EZH2, EED and an inhibitor of choice. Next, incubate with a mixture of acceptor and donor beads, followed by reading the Alpha-counts.
Useful for the study of EZH2 binding assays, screening inhibitors and selectivity profiling.
At least one year from date of receipt when stored as directed.
EZH2, GST-tag: 20 µg; -80°CEED, FLAG-tag: 10 µg; -80°C 4x HMT Assay Buffer 2: 4 ml; -20°C