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Ganglioside GM2 (sodium salt)

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By Species
Bovine(1)
By Source
Cat.No.:
GM2-9001
Product Overview:
Ganglioside GM2 (sodium salt) is isolated from bovine brain.
Description:
Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GM2 is a very minor component of the nervous system, but it is accumulated in brains from Tay-Sachs and Sandhoff disease patients, due to genetic defect of lysosomal β-hexosaminidase.
Source:
Bovine brain
Species:
Bovine
Form:
Lyophilized
Molecular Mass:
1406.7
Endotoxin:
Not detectable.
Purity:
>98% (TLC)
Stability:
Stable for at least 2 years after receipt when stored at -20°C.
Storage:
Short Term Storage +4°C
Long Term Storage -20°C
Dilutions:
Soluble in water (liposomal aggregates) or chloroform:methanol (2:1).
Shipping:
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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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