Recombinant Human AXL protein, GST-tagged

Cat.No.: AXL-379H
Product Overview: Recombinant Human AXL(464-885(end)) fused with GST tag at N-terminal was expressed in Insect cells.
Description: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.
Source: Insect cells
Species: Human
Tag: GST
Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
Molecular Mass: 74 kDa
Purity: 0.66
Storage: Store at -80 centigrade.Avoid repeating freeze-thaws.
Gene Name: AXL AXL receptor tyrosine kinase [ Homo sapiens ]
Official Symbol: AXL
Synonyms: AXL; AXL receptor tyrosine kinase; tyrosine-protein kinase receptor UFO; JTK11; UFO; AXL oncogene; oncogene AXL; AXL transforming sequence/gene;
Gene ID: 558
mRNA Refseq: NM_001699
Protein Refseq: NP_001690
MIM: 109135
UniProt ID: P30530
Chromosome Location: 19q13.1
Function: ATP binding; nucleotide binding; protein heterodimerization activity; receptor activity; transmembrane receptor protein tyrosine kinase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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