Recombinant Human BCL2 protein, His-tagged
Cat.No. : | BCL2-266H |
Product Overview : | Recombinant Human BCL2(Ala2~Asp211) fused with His tag at C-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300 |
Molecular Mass : | 27kDa |
Protein length : | Ala2~Asp211 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Reconstitution : | Reconstitute in PBS or others. |
Gene Name : | BCL2 B-cell CLL/lymphoma 2 [ Homo sapiens ] |
Official Symbol : | BCL2 |
Synonyms : | BCL2; B-cell CLL/lymphoma 2; apoptosis regulator Bcl-2; Bcl 2; PPP1R50; protein phosphatase 1; regulatory subunit 50; protein phosphatase 1, regulatory subunit 50; Bcl-2; |
Gene ID : | 596 |
mRNA Refseq : | NM_000633 |
Protein Refseq : | NP_000624 |
UniProt ID : | P10415 |
Chromosome Location : | 18q21.3 |
Pathway : | ATF-2 transcription factor network, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; |
Function : | BH3 domain binding; channel activity; identical protein binding; protease binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein phosphatase 2A binding; sequence-specific DNA binding; transcription factor binding; ubiquitin protein ligase binding; |
Products Types
◆ Recombinant Protein | ||
BCL2-2469H | Recombinant Human BCL2 Protein, MYC/DDK-tagged | +Inquiry |
BCL2-615R | Recombinant Rat BCL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
BCL2-22H | Recombinant Human BCL2 Protein | +Inquiry |
BCL2-1346H | Recombinant Human BCL2 Protein, His-tagged | +Inquiry |
Bcl2-304R | Recombinant Rat Bcl2 Protein, His-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1686 | BCL-2 TR-FRET Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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