Recombinant Human COX20 fused with MYC/DDK tag at C-terminal was expressed in HEK293.
This gene encodes a protein that plays a role in the assembly of cytochrome C oxidase, an important component of the respiratory pathway. It contains two transmembrane helices and localizes to the mitochondrial membrane. Mutations in this gene can cause mitochondrial complex IV deficiency, which results in ataxia and muscle hypotonia. There are multiple pseudogenes for this gene. Alternative splicing results in multiple transcript variants.
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles.
> 80% as determined by SDS-PAGE and Coomassie blue staining
Stable for at least 3 months from receipt of products under proper storage and handling conditions.
>50 ug/mL as determined by microplate BCA method