Recombinant human ESM1 gene cDNA (19 - 184aa, Isoform-I, derived from BC011989) fused with T7-His-TEV cleavage site Tag (29aa) at N-terminal was expressed in E. coli.
1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol.
MASMTGGQQMGRGHHHHHHGNLYFQGGEFWSNNYAVDCPQHCDSSECKSSPRCERTVLDDCGCCRVCAAGRGETC YRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQYSVT KSSNRFVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKWLNPR
1. May be used for in vitro ESM1 mediated endothelial cell differentiation regulation study with this protein as either coating matrix protein or soluble factor.2. May be used as EMS1 protein-protein interaction assay.3. As enzymatic substrate for various proteases.4. Potential biomarker protein for cancer diagnosis, such as for human lung cancer and renal clear cell carcinoma. MSE1 may also be a potential parameter to monitor the tumor response to anti-angiogenic5. As antigen for specific antibody production.
Keep at -80centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days.