Recombinant Human GDF11 protein

• Cat.No.: GDF11-01H
• Product Overview: Recombinant Human GDF11 was expressed in E. coli.

Specification

• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging.
• Source: E. coli
• Species: Human
• Form: 20mM Tris-HCl, 200 mM NaCl, pH7.4, 2Mm DTT
• Molecular Mass: ~13 kDa
• AA Sequence: NLGLDCDEHSSESRCCRYPLTVDFE AFGWDWIIAPKRYKANYCSGQCEYM FMQKYPHTHLVQQANPRGSAGPCCT PKMSPINMLYFNDKQQIIYGKIPGM VVDRCGCS
• Purity: > 95% as determined by SDS-PAGE
• Storage: Short Term Storage (1 week) at +4 centigrade, Long Term Storage(3 months) at -20 centigrade to -80 centigrade. Avoid freeze/thaw cycles.
• Concentration: 0.1 mg/ml

Gene Information

• Gene Name: GDF11 growth differentiation factor 11 [ Homo sapiens ]
• Official Symbol: GDF11
• Synonyms: GDF11; growth differentiation factor 11; growth/differentiation factor 11; BMP 11; GDF-11; bone morphogenetic protein 11; BMP11; BMP-11
• Gene ID: 10220
• mRNA Refseq: NM_005811
• Protein Refseq: NP_005802
• MIM: 603936
• UniProt ID: O95390
• Chromosome Location: 12q13.13
• Function: cytokine activity; growth factor activity