Recombinant Human HIF1A protein, His/S-tagged
Cat.No. : | HIF1A-155H |
Product Overview : | Recombinant Human HIF1A fused with His/S tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator(ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. |
Source : | E. coli |
Species : | Human |
Tag : | His/S |
Form : | Lyophilized from sterile PBS, pH 7.4 |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | Store at -70 centigrade. Avoid repeated freeze/thaw cycles. |
Gene Name : | HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) [ Homo sapiens ] |
Official Symbol : | HIF1A |
Synonyms : | HIF1A; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1-alpha; bHLHe78; HIF 1alpha; HIF1; MOP1; PASD8; HIF-1-alpha; member of PAS protein 1; ARNT interacting protein; ARNT-interacting protein; member of PAS superfamily 1; PAS domain-containing protein 8; basic-helix-loop-helix-PAS protein MOP1; class E basic helix-loop-helix protein 78; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); HIF-1alpha; HIF1-ALPHA; |
Gene ID : | 3091 |
mRNA Refseq : | NM_001243084 |
Protein Refseq : | NP_001230013 |
MIM : | 603348 |
UniProt ID : | Q16665 |
Chromosome Location : | 14q23.2 |
Pathway : | Adipogenesis, organism-specific biosystem; Angiogenesis, organism-specific biosystem; Circadian Clock, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; Hypoxic and oxygen homeostasis regulation of HIF-1-alpha, organism-specific biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem; |
Function : | Hsp90 protein binding; histone acetyltransferase binding; histone deacetylase binding; protein binding; protein heterodimerization activity; protein heterodimerization activity; protein kinase binding; contributes_to sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; contributes_to sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; signal transducer activity; transcription factor binding; transcription regulatory region DNA binding; |
Products Types
◆ Recombinant Protein | ||
HIF1A-3111H | Recombinant Human HIF1A Protein, His (Fc)-Avi-tagged | +Inquiry |
HIF1A-0487H | Recombinant Human HIF1A Protein (E2-N826), His/Strep tagged | +Inquiry |
HIF1A-2496R | Recombinant Rat HIF1A Protein, His (Fc)-Avi-tagged | +Inquiry |
HIF1A-2240H | Recombinant Human HIF1A Protein, His-tagged | +Inquiry |
HIF1A-0486H | Recombinant Human HIF1A Protein (E2-N826), Tag Free | +Inquiry |
◆ Lysates | ||
HIF1A-787HCL | Recombinant Human HIF1A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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