Recombinant Human LAMA3 & LAMB3 & LAMC2 was purified from 184A1 human mammary epithelial cell conditioned media. Filter Sterile, both processed and unprocessed forms are present.
Laminin 332 (formerly laminin 5) is a heterotrimeric basement membrane protein composed of the alpha3, beta3 and gamma2 chains of laminin. It is expressed in skin, breast and other tissues, where it is involved in formation of hemidesmosomes and wound healing. Laminin 332 has been implicated in cancer progression. In breast cancer, laminin 332 has been identified as a microenvironmental protein which can act as a motility factor.
184A1 human mammary epithelial cell conditioned media
150 mM NaCl, 10 mM Tris, pH 7.4
10 ug/mL will induce scattering of 50% of MCF-7 cells after 24 hour incubation.
450 kDa, unprocessed
Approximately 90%, Assessed by SDS PAGE.
Storage Temperature: -20 centigrade or lower (Thawed protein retains activity for 1 month if stored at 4 centigrade).