Recombinant Human PKN1 protein, Flag-tagged, Biotinylated

• Cat.No.: PKN1-72H
• Product Overview: Recombinant Human PKN1 [1-942(end) amino acids of accession number NP_002732.3] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.

Specification

• Source: Insect cell
• Species: Human
• Tag: Flag
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 108 kDa
• Purity: >90% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: PKN1 protein kinase N1 [ Homo sapiens ]
• Official Symbol: PKN1
• Synonyms: PKN1; DBK; MGC46204; PAK1; PKN; PRK1; protein kinase C-like 1; protein kinase PKN-alpha; serine-threonine kinase N; PAK-1; PRKCL1; PKN-ALPHA
• Gene ID: 5585
• mRNA Refseq: NM_002741
• Protein Refseq: NP_002732
• MIM: 601032
• UniProt ID: Q16512
• Chromosome Location: 19p13.12
• Pathway: G13 Signaling Pathway, organism-specific biosystem; Regulation of Androgen receptor activity, organism-specific biosystem; RhoA signaling pathway, organism-specific biosystem; Salmonella infection, organism-specific biosystem; Salmonella infection, conserved biosystem; Signaling mediated by p38-gamma and p38-delta, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem
• Function: ATP binding; GTP-Rho binding; Rac GTPase binding; androgen receptor binding; chromatin binding; histone binding; histone deacetylase binding; histone kinase activity (H3-T11 specific); ligand-dependent nuclear receptor transcription coactivator activity; ligand-dependent nuclear receptor transcription coactivator activity; nucleotide binding; protein binding; protein kinase C activity; protein kinase C binding; protein kinase activity; protein serine/threonine kinase activity