"SNRPA" Related Products

Recombinant Human SNRPA protein, His-tagged

Cat.No.: SNRPA-493H
Product Overview: Recombinant Human SNRPA(8-278 aa) fused with His tag at N-terminal was expressed in E. coli.
Description: The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
Source: E. coli
Species: Human
Tag : His
AA Sequence: PNHTIYINNL NEKIKKDELK KSLYAIFSQF GQILDILVSR SLKMRGQAFV IFKEVSSATN ALRSMQGFPF YDKPMRIQYA KTDSDIIAKM KGTFVERDRK REKRKPKSQE TPATKKAVQG GGATPVVGAV QGPVPGMPPM TQAPRIMHHM PGQPPYMPPP GMIPPPGLAP GQIPPGAMPP QQLMPGQMPP AQPLSENPPN HILFLTNLPE ETNELMLSML FNQFPGFKEV RLVPGRHDIA FVEFDNEVQA GAARD
Purity: Greater than 90% as determined by SDS-PAGE.
Storage: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade.
Gene Name: SNRPA small nuclear ribonucleoprotein polypeptide A [ Homo sapiens ]
Official Symbol: SNRPA
Synonyms: SNRPA; small nuclear ribonucleoprotein polypeptide A; U1 small nuclear ribonucleoprotein A; Mud1; U1 A; U1A; U1 snRNP A; U1 snRNP-specific protein A; U1 small nuclear RNP-specific A; U1-A;
Gene ID: 6626
mRNA Refseq: NM_004596
Protein Refseq: NP_004587
MIM: 182285
UniProt ID: P09012
Chromosome Location: 19q13.1
Pathway: Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; Spliceosome, U1-snRNP, organism-specific biosystem; mRNA Splicing, organism-specific biosystem; mRNA Splicing - Major Pathway, organism-specific biosystem;
Function: RNA binding; nucleotide binding; protein binding; snRNA binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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