Recombinant Human SOD1 protein, His/MBP-tagged
Cat.No. : | SOD1-328H |
Product Overview : | Recombinant Human SOD1 fused with His/MBP tag was expressed in E. coli. |
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Description : | The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His/MBP |
Form : | Liquid in PBS |
Purity : | SDS-PAGE >90% |
Applications : | WB Positive Control |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | SOD1 superoxide dismutase 1, soluble [ Homo sapiens ] |
Official Symbol : | SOD1 |
Synonyms : | SOD1; superoxide dismutase 1, soluble; ALS, ALS1, amyotrophic lateral sclerosis 1 (adult); superoxide dismutase [Cu-Zn]; IPOA; SOD, soluble; indophenoloxidase A; Cu/Zn superoxide dismutase; superoxide dismutase, cystolic; ALS; SOD; ALS1; hSod1; homodimer; |
Gene ID : | 6647 |
mRNA Refseq : | NM_000454 |
Protein Refseq : | NP_000445 |
MIM : | 147450 |
UniProt ID : | P00441 |
Products Types
◆ Recombinant Protein | ||
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SOD1-5325R | Recombinant Rat SOD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SOD1-1158H | Recombinant Human SOD1 Protein, MYC/DDK-tagged | +Inquiry |
SOD1-67H | Recombinant Human SOD1 Protein | +Inquiry |
SOD1-1037H | Recombinant Human SOD1 Protein | +Inquiry |
◆ Native Protein | ||
SOD1-101B | Active Native Bovine SOD | +Inquiry |
CED026 | Active Bovine Superoxide Dismutase (SOD), High Purity >95% | +Inquiry |
SOD1-102B | Active Native Bovine SOD, modified | +Inquiry |
◆ Lysates | ||
SOD1-1576HCL | Recombinant Human SOD1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionTherapeutic strategies may involve modulating SOD1 activity or expression to mitigate oxidative stress-related damage.
SOD1 acts as an antioxidant, converting superoxide radicals to hydrogen peroxide and oxygen.
Mutations in SOD1 can result in loss or gain of function, contributing to disease development.
SOD1 mutations are implicated in Amyotrophic Lateral Sclerosis (ALS), leading to neurodegeneration.
SOD1 is primarily located in the cytoplasm and mitochondrial intermembrane space.
It helps maintain cellular redox balance, protecting cells from oxidative damage.
It plays a crucial role in cellular defense against oxidative stress.
Customer Reviews (3)
Write a reviewWorked perfectly, no problems.
Quick delivery, fantastic product.
Reliable results every time.
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