Recombinant Human TNFAIP3 protein, MYC/DDK-tagged
Cat.No. : | TNFAIP3-159H |
Product Overview : | Recombinant Human TNFAIP3 fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 89.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Notes : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Concentration : | >50 ug/mL as determined by microplate BCA metho |
Gene Name : | TNFAIP3 tumor necrosis factor, alpha-induced protein 3 [ Homo sapiens ] |
Official Symbol : | TNFAIP3 |
Synonyms : | TNFAIP3; tumor necrosis factor, alpha-induced protein 3; tumor necrosis factor alpha-induced protein 3; A20; OTUD7C; TNFAIP3 (A20); zinc finger protein A20; TNF alpha-induced protein 3; OTU domain-containing protein 7C; putative DNA-binding protein A20; tumor necrosis factor inducible protein A20; TNFA1P2; MGC104522; MGC138687; MGC138688; |
Gene ID : | 7128 |
mRNA Refseq : | NM_006290 |
Protein Refseq : | NP_006281 |
MIM : | 191163 |
UniProt ID : | P21580 |
Chromosome Location : | 6q23-q25 |
Pathway : | CD40/CD40L signaling, organism-specific biosystem; Canonical NF-kappaB pathway, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Measles, organism-specific biosystem; Measles, conserved biosystem; NOD-like receptor signaling pathway, organism-specific biosystem; |
Function : | DNA binding; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; cysteine-type peptidase activity; kinase binding; ligase activity; metal ion binding; peptidase activity; protease binding; protein binding; protein self-association; ubiquitin binding; ubiquitin thiolesterase activity; ubiquitin-protein ligase activity; ubiquitin-specific protease activity; ubiquitin-specific protease activity; zinc ion binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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