Recombinant Human WHSC1 protein, FLAG/His-tagged
Cat.No. : | WHSC1-185H |
Product Overview : | Recombinant Human WHSC1(782-end) fused with FLAG/His tag at N-terminal was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | NSD2 is a histone methyltransferase that preferentially methylates Lys27 of histone H3. Isoform RE-IIBP may act as a transcription regulator that binds DNA and suppresses IL5 transcription through HDAC recruitment. Mutations in the gene for NSD2 are linked to Wolf-Hirschhorn syndrome (WHS), a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4, and is also associated with chromosomal translocations in multiple myelomas. |
Source : | Insect cells |
Species : | Human |
Tag : | FLAG/His |
Form : | 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM, 10% glycerol, 90 µg/ml FLAG peptide and 3 mM DTT. |
Molecular Mass : | 66.5 kDa |
Purity : | >30% |
Applications : | Suitable for protein binding studies, as an immunogen, or as a Western blotting control. |
Storage : | >6 months at -80 centigrade. Avoid freeze/thaw cycles. |
Concentration : | 0.09 mg/ml |
Gene Name : | WHSC1 Wolf-Hirschhorn syndrome candidate 1 [ Homo sapiens ] |
Official Symbol : | WHSC1 |
Synonyms : | WHSC1; Wolf-Hirschhorn syndrome candidate 1; probable histone-lysine N-methyltransferase NSD2; MMSET; NSD2; trithorax/ash1-related protein 5; nuclear SET domain-containing protein 2; IL5 promoter REII region-binding protein; multiple myeloma SET domain containing protein type III; WHS; TRX5; REIIBP; FLJ23286; KIAA1090; MGC176638; |
Gene ID : | 7468 |
mRNA Refseq : | NM_133330 |
Protein Refseq : | NP_579877 |
MIM : | 602952 |
UniProt ID : | O96028 |
Chromosome Location : | 4p16.3 |
Pathway : | Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem; |
Function : | DNA binding; histone-lysine N-methyltransferase activity; metal ion binding; methyltransferase activity; transferase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
WHSC1-10177M | Recombinant Mouse WHSC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
WHSC1-146H | Recombinant Human WHSC1(E1099K) Protein, His-tagged | +Inquiry |
WHSC1-144H | Recombinant Human WHSC1 Protein, His-tagged | +Inquiry |
WHSC1-145H | Recombinant Human WHSC1 Protein | +Inquiry |
WHSC1-429H | Recombinant Human Wolf-Hirschhorn Syndrome Candidate 1, GST-tagged | +Inquiry |
◆ Lysates | ||
WHSC1-1931HCL | Recombinant Human WHSC1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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