Recombinant Mouse Ager protein, His & T7-tagged
Cat.No. : | Ager-653M |
Product Overview : | Recombinant Mouse Ager aa. (Trp10~Arg188 (Accession # Q62151)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
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Source : | E. coli |
Species : | Mouse |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 23.3kDa |
Protein length : | Trp10~Arg188 (Accession # Q62151) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 9.5. |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | Ager advanced glycosylation end product-specific receptor [ Mus musculus (house mouse) ] |
Official Symbol : | Ager |
Synonyms : | Ager; advanced glycosylation end product-specific receptor; RAGE; advanced glycosylation end product-specific receptor; advanced glycation end-products receptor; receptor for advanced glycation end-products variant 20; receptor for advanced glycosylation end products |
Gene ID : | 11596 |
mRNA Refseq : | NM_001271422.1 |
Protein Refseq : | NP_001258351.1 |
UniProt ID : | Q62151 |
Products Types
◆ Recombinant Protein | ||
Ager-3304M | Recombinant Mouse Ager protein(Met1-Ala342), His-tagged | +Inquiry |
Ager-712M | Recombinant Mouse Ager Protein, His-tagged | +Inquiry |
Ager-2R | Recombinant Rat Ager Protein, His (Fc)-Avi-tagged | +Inquiry |
Ager-713R | Recombinant Rat Ager Protein, His/GST-tagged | +Inquiry |
Ager-3M | Recombinant Mouse Ager Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
AGER-2215MCL | Recombinant Mouse AGER cell lysate | +Inquiry |
AGER-1480HCL | Recombinant Human AGER cell lysate | +Inquiry |
AGER-2546HCL | Recombinant Human RAGE 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (20)
Ask a questionAGER is involved in bone metabolism and might influence osteoporosis and bone diseases.
AGER levels might serve as biomarkers for certain diseases, including diabetes.
AGER binds AGEs, initiating signaling cascades linked to inflammation, oxidative stress, and tissue damage.
AGER contributes to skin aging through oxidative stress and collagen damage.
AGER stands for "Advanced Glycosylation End-Product Specific Receptor," a cell surface receptor.
Yes, AGER activation contributes to inflammation and immune responses.
AGER activation can impair wound healing through inflammation and oxidative stress.
AGER contributes to neuroinflammation and might play a role in neurodegeneration.
AGER contributes to diabetic nephropathy and kidney dysfunction.
AGER binds to AGEs, initiating cellular signaling pathways linked to inflammation and oxidative stress.
AGER is implicated in lung diseases and inflammation, such as chronic obstructive pulmonary disease.
Researchers explore compounds that modulate AGER to mitigate its effects.
AGER contributes to diabetic complications by promoting inflammation and tissue damage.
AGER is studied for its implications in aging, diabetes, and various age-related diseases.
AGER plays a role in mediating cellular responses to advanced glycation end products (AGEs).
Consuming a low-AGE diet may help reduce AGER activation and its negative effects.
AGER activation affects immune cell functions and influences immune responses.
AGER activation is linked to cardiovascular diseases, including atherosclerosis.
Yes, besides AGEs, AGER interacts with other ligands like HMGB1 and β-amyloid.
Yes, ongoing research aims to uncover new roles and therapeutic targets related to AGER.
Customer Reviews (5)
Write a reviewIt's quality was evident in consistent results across replicates.
Protein consistently upregulated the expression of tissue-specific markers.
Gel electrophoresis bands displayed distinct separation, showcasing the product’s purity.
It’s consistent outcomes supported reliable statistical analysis.
Consistency and Compatibility Consistency in the product’s performance bolstered the credibility of our research findings.
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