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Recombinant Mouse Cd47 protein, His-tagged

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Product Name:
Recombinant Mouse Cd47 protein, His-tagged
Product Overview:
Recombinant mouse CD47(NP_034711.1)(Gln19-Ala140) fused with His tag at C-terminal was expressed in HEK293.
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.
Lyophilized from 0.2μm-filtered solution in PBS.
Molecular Mass:
The predicted molecular mass is 15kDa, and the apparent molecular mass is approximately 35kDa in SDS-PAGE under reducing conditions.
<1 EU/μg as determined by LAL test.
>95%,by SDS-PAGE under reducing conditions
Stable for at least 1 year after receipt when stored at -20 centigrade. Working aliquots are stable for up to 3 months when stored at -20 centigrade.
Reconstitute at 100μg/ml in sterile PBS.

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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127

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