Active Recombinant Mouse Sparcl1 protein, His-tagged

• Cat.No.: Sparcl1-877M
• Product Overview: Recombinant Mouse Sparcl1 protein(NP_034227.3)(Tyr368-Phe650), fused with His tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Mouse
• Tag: His
• Form: Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Bio-activity: Measured by its ability to inhibit the cell growth of Mv-1-Lu mink lung epithelial cells. The ED50 for this effect is typically 1-4 μg/mL.
• Molecular Mass: The recombinant mouse Sparcl1 consists 302 amino acids and predicts a molecular mass of 34.8 kDa.
• Protein Length: Tyr368-Phe650
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 90 % as determined by SDS-PAGE.
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: Sparcl1 SPARC-like 1 [ Mus musculus ]
• Official Symbol: Sparcl1
• Synonyms: SPARCL1; SPARC-like 1; SPARC-like protein 1; matrix glycoprotein Sc1; SPARC-like 1 (mast9, hevin); extracellular matrix protein 2; Sc1; Ecm2; hevin; mast9
• Gene ID: 13602
• mRNA Refseq: NM_010097
• Protein Refseq: NP_034227

Reviews

10/14/2022

The bands of proteins in Western Blotting experiments were very clear.

06/15/2022

Researchers can rely on the SPARCL1 protein to deliver precise results, enhancing the credibility and efficiency of their experiments.

01/24/2018

The SPARCL1 protein is highly recommended for its exceptional performance in ELISA assays.

Q&As

How does SPARCL1 influence cell adhesion and migration?

SPARCL1 interacts with cell adhesion molecules and the extracellular matrix, influencing cell adhesion and migration in various physiological processes.

How is SPARCL1 linked to wound healing?

SPARCL1 is involved in tissue repair and wound healing processes, influencing cell migration, adhesion, and extracellular matrix remodeling.

Can SPARCL1 be used as a predictive marker for patient outcomes in cancer?

Studies suggest that low SPARCL1 expression is associated with poor prognosis in certain cancers, indicating its potential as a predictive marker.

Are there therapeutic implications for modulating SPARCL1 expression?

Modulating SPARCL1 expression could be a potential therapeutic strategy, particularly in cancer treatment, by targeting tumor progression or metastasis.

In which types of cancer is SPARCL1 often downregulated?

SPARCL1 is frequently downregulated in breast, lung, and colorectal cancers, suggesting a potential role as a prognostic marker.