Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email: info@creative-biomart.com
Home > Products > Recombinant Proteins > Recombinant Rat Dyrk1a protein, GST-tagged

Recombinant Rat Dyrk1a protein, GST-tagged

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GST(2)
His(3)
Cat.No.:
Dyrk1a-1990R
Product Overview:
Recombinant Rat Dyrk1a fused with GST tag at N-terminal was expressed in E. coli.
Description:
DYRK1 A or dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A is a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family which contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. DYRK1A participates in various cellular processes. DYRK1A is a highly conserved gene located in the so-called Down Syndrome critical region (DSCR) on part of chromosome 21 that is responsible for the majority of phenotypic features in Down syndrome (1). DYRK1A plays a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. DYRK1A is also contributing to early onset of Alzheimer disease.
Source:
E. coli
Species:
Rat
Tag :
GST
Form:
50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity:
1200 nmol/min/mg
Molecular Mass:
~100 kDa
Purity:
>70%
Applications:
Kinase Assay, Western Blot
Stability:
1 year at -70 centigrade from the date of shipment
Storage:
Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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