Ac-DEVD-AFC
Cat.No. : | DYE-120 |
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Description : | During apoptosis, activated caspase-3 cleaves several substrates, including poly (ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-AFC is a fluorogenic substrate for activated caspase-3 (Km = 9.7 μM), as well as related caspases. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. |
Molecular Mass : | 729.61 |
Ex(nm) : | 351 |
Em(nm) : | 430 |
Solvent : | DMSO |
Storage : | Store at -20°C in the dark. Dessicated. |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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