Ac-IETD-AMC
| Cat.No. : | DYE-127 |
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| Description : | Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. This substrate is hydrlyzed by caspase 8 to generate highly fluorescent 7-amido-4-methylcoumarin (AMC). |
| Molecular Mass : | 675.68 |
| Ex(nm) : | 351 |
| Em(nm) : | 430 |
| Solvent : | DMSO |
| Storage : | Store at -20°C in the dark. Dessicated. |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionThe AC-IETD-AMC assay requires a fluorescence plate reader to measure the amount of fluorescence produced, but it does not require any special cuvettes.
The AC-IETD-AMC assay is specific for caspase-8 activity, as the substrate used in the assay is only cleaved by this particular enzyme.
The AC-IETD-AMC assay can be used with a variety of biological samples, including tissue lysates, cell culture supernatants, and purified protein preparations.
The AC-IETD-AMC assay works by measuring the amount of fluorescence produced when caspase-8 cleaves the AMC substrate.
AC-IETD stands for the specific amino acid sequence in the substrate that is cleaved by caspase-8.
The purpose of the AC-IETD-AMC assay is to measure the activity of caspase-8 in biological samples.
The full name of the substrate AMC is 7-amino-4-methylcoumarin.
Customer Reviews (3)
Write a reviewThe customer service staff are very responsible and deal with problems in a timely manner.
Detection is very precise. Easy to use.
Professional supplier with guaranteed quality.
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