Active GMP Recombinant Human MSLN protein
Cat.No. : | MSLN-976HG |
Product Overview : | GMP Recombinant Human MSLN protein(NP_001170826)(284 aa), fused with His Tag at the C-terminal, was expressed in HEK293 cell in an animal component free process under cGMP guidelines. |
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Source : | HEK293 |
Species : | Human |
Form : | Freeze-dried powder contains Sterile PBS (pH 7.4) with 6% mannitol. |
Bio-activity : | The linear range of immobilized Human Mesothelin (His Tag) at 1ug/ml (100 uL/well) that can bind to Anti-human MSLN monoclonal antibody is 0.05-5ng/mL. |
Molecular Mass : | Recombinant Human MSLN protein contains284aa. It has a predicted MW of 33.7kDa. |
Protein length : | DNA sequence encoding Human MSLN(GenBank: AAH09272.1) was expressed with His tag at the C-terminal. |
Endotoxin : | <0.05EU/ug |
Purity : | >=95% by SDS-PAGE and HPLC |
Storage : | The lyophilized preparation can be stored at 4°C for 24 months, and the dissolved liquid can be stored at -20°C for 6-12 months to avoid repeated freezing and thawing |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | MSLN mesothelin [ Homo sapiens ] |
Official Symbol : | MSLN |
Synonyms : | MSLN; Mesothelin; MPF |
Gene ID : | 10232 |
mRNA Refseq : | NM_001177355 |
Protein Refseq : | NP_001170826 |
MIM : | 601051 |
UniProt ID : | Q13421 |
Products Types
◆ Recombinant Protein | ||
MSLN-10625H | Active Recombinant Human MSLN Protein, Fc-tagged | +Inquiry |
MSLN-001H | Active Recombinant Human MSLN Protein, His-tagged | +Inquiry |
MSLN-2457H | Recombinant Human MSLN Protein, His-tagged | +Inquiry |
MSLN-3297H | Recombinant Human MSLN protein(Glu296-Gly580), His-tagged | +Inquiry |
MSLN-382H | Recombinant Human MSLN Protein, His-tagged | +Inquiry |
◆ Lysates | ||
MSLN-1316HCL | Recombinant Human MSLN cell lysate | +Inquiry |
MSLN-1343HCL | Recombinant Human MSLN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMSLN is normally expressed in mesothelial cells, playing a role in cell adhesion.
In cancer, MSLN expression is significantly upregulated.
MSLN is overexpressed in mesothelioma, ovarian, and pancreatic cancers.
Therapies targeting MSLN include antibody-drug conjugates and CAR-T cell therapies.
MSLN levels can be assessed through immunohistochemistry and serum biomarker tests.
MSLN overexpression is often associated with poor prognosis in cancer patients.
MSLN promotes tumor cell proliferation, invasion, and resistance to apoptosis.
Customer Reviews (3)
Write a reviewVery satisfied, great product.
Product is high-quality.
Excellent for experiments, reliable.
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