Active MSLN protein-coupled magnetic Beads
Cat.No. : | MSLN-7689M |
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Species : | Human |
Appearance : | Powder mixture |
Particle size : | 2 μm |
Source : | HEK293 |
Protein Length : | Glu 296 - Gly 580 (R309P) |
Bio-activity : | Immobilized 19.5 μg MSLN to 1mg Beads can bind the Anti MSLN Ab with an EC50 of 0.1037 μg/mL. |
Coupled amount of protein : | ≈330 pmol (19.5μg) Mesothelin / mg beads |
Capacity : | >270 pmol (16 ug) Anti-hMSLN antibody / mg beads |
Formulation : | PBS, pH7.4, with 10% Trehalose |
Reconstitution : | 2 mL sterile deionized water (1 mg beads/mL) |
Background : | The Human Mesothelin-coupled Magnetic Beads is produced by coupling biotinylated mesothelin protein to streptavidin-conjugated magnetic beads. Because Streptavidin (SA) has an extraordinarily high affinity for biotin with a dissociation constant (Kd) on the order of 10-14 mol/L, the biotinylated protein can bind to the SA beads irreversibly. The pre-coupled beads are ready to use for capturing anti-mesothelin antibody from your sample with high specificity. |
Application : | This product is intended for immunocapture, biopanning and flow cytometry. This product is produced non-sterile. |
Storage : | Upon receipt, please store the Beads at -20°C for 1 year in lyophilized state. |
Products Types
◆ Recombinant Protein | ||
MSLN-3527H | Recombinant Human MSLN Protein, His (Fc)-Avi-tagged | +Inquiry |
MSLN-15H | Active Recombinant Human MSLN Protein, His-tagged, Alexa Fluor® 488 conjugated | +Inquiry |
MSLN-8392H | Active Recombinant Human MSLN Protein | +Inquiry |
MSLN-10625H | Active Recombinant Human MSLN Protein, Fc-tagged | +Inquiry |
MSLN-381H | Recombinant Human MSLN Protein, His-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
MSLN-1316HCL | Recombinant Human MSLN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMSLN is normally expressed in mesothelial cells, playing a role in cell adhesion.
In cancer, MSLN expression is significantly upregulated.
MSLN is overexpressed in mesothelioma, ovarian, and pancreatic cancers.
Therapies targeting MSLN include antibody-drug conjugates and CAR-T cell therapies.
MSLN levels can be assessed through immunohistochemistry and serum biomarker tests.
MSLN overexpression is often associated with poor prognosis in cancer patients.
MSLN promotes tumor cell proliferation, invasion, and resistance to apoptosis.
Customer Reviews (3)
Write a reviewVery satisfied, great product.
Product is high-quality.
Excellent for experiments, reliable.
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