Active Recombinant Cynomolgus CYP3A4 Protein
Cat.No. : | CYP3A4-128C |
Product Overview : | Recombinant cynomolgus CYP3A4 protein and human CYP-reductase without tag were coexpressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Catalyzes nifedipine and nilvadipine oxidations. |
Source : | E. coli |
Species : | Cynomolgus |
Bio-activity : | Cytochrome c Reductase Activity: 171 nmol/min/mg protein P450 Activity Data(Unless otherwise stated, all assays are carried out at 37 centigrade in 100 mM potassium phosphate buffer (pH 7.4) containing 5 mM magnesium chloride and an NADPH generating system [5 mM glucose 6-phosphate, 1 mM NADP+, 1 U/ml glucose 6-phosphate dehydrogenase]) Activity: Testosterone 6β-hydroxylase Linear with time up to: 15 min(Determined at 15 µM substrate, using a P450 concentration of 25 pmol/ml) Linear with P450 up to: 60 pmol/ml(Determined at 15 µM substrate, using an incubation time of 5 min) Vmax: 4.8 pmol/min/pmol CYP Km: 17 μM |
Usage : | For laboratory (research) purposes only |
Storage : | Store at -80 centigrade. Avoid frequent temperature changes. Thaw on ice. |
Concentration : | P450 Concentration: 5.0 nmol/ml Protein Concentration: 11.7 mg/ml Specific P450 Content: 427 pmol/mg protein |
Storage Buffer : | 50 mM Tris-acetate (pH 7.6), 250 mM sucrose, 0.25 mM EDTA |
Gene Name : | CYP3A4 cytochrome P450 family 3 subfamily A member 4 [ Macaca fascicularis (crab-eating macaque) ] |
Official Symbol : | CYP3A4 |
Synonyms : | CYP3A4; cytochrome P450 family 3 subfamily A member 4; CYP3A8; CYPIIIA8; cytochrome P450 3A8; Cytochrome P-450-MK2; Cytochrome P450 3A8; Cytochrome P450-MKNF2; P-450 3A; cytochrome P-450 3A |
Gene ID : | 102144258 |
mRNA Refseq : | NM_001284534 |
Protein Refseq : | NP_001271463 |
UniProt ID : | P33268 |
Products Types
◆ Recombinant Protein | ||
CYP3A4-81H | Active Recombinant Human CYP3A4 Protein | +Inquiry |
CYP3A4-2273H | Recombinant Human CYP3A4 Protein, GST-tagged | +Inquiry |
CYP3A4-1301H | Recombinant Human CYP3A4 Protein, His-tagged | +Inquiry |
CYP3A4-347H | Active Recombinant Human CYP3A4 Protein | +Inquiry |
CYP3A4-983R | Recombinant Rhesus Macaque CYP3A4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CYP3A4-436HCL | Recombinant Human CYP3A4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1918 | Cytochrome P450 3A4 (CYP3A4) Activity Assay Kit | +Inquiry |
Kit-2142 | Cytochrome P450 3A4 Inhibitor Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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