Active Recombinant Full Length Human BMI1 Protein, N-His-tagged
Cat.No. : | BMI1-427HFL |
Product Overview : | Recombinant Full Length Human BMI1 Protein, fused to His-tag at N-terminus, was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 100 mM Arg. |
Bio-activity : | In vitro kinase assay substrate Binding assay (competitor) |
Molecular Mass : | 36.9 kDa |
AA Sequence : | A DNA sequence encoding human full-length BMI1. |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors |
Gene Name : | BMI1 BMI1 proto-oncogene, polycomb ring finger [ Homo sapiens (human) ] |
Official Symbol : | BMI1 |
Synonyms : | PCGF4; RNF51; FLVI2/BMI1; flvi-2/bmi-1 |
Gene ID : | 648 |
mRNA Refseq : | NM_005180.9 |
Protein Refseq : | NP_005171.4 |
MIM : | 164831 |
UniProt ID : | P35226 |
Products Types
◆ Recombinant Protein | ||
BMI1-27487H | Recombinant Human BMI1, GST-tagged | +Inquiry |
BMI1-1049M | Recombinant Mouse BMI1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMI1-316H | Recombinant Human BMI1 Protein, His-tagged | +Inquiry |
BMI1-771H | Recombinant Human BMI1 Protein, His tagged | +Inquiry |
BMI1-2733H | Recombinant Human BMI1 protein(101-170 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
BMI1-8437HCL | Recombinant Human BMI1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket