Active Recombinant Full Length Human CHI3L1 Protein, C-Flag-tagged

• Cat.No.: CHI3L1-347HFL
• Product Overview: Recombinant Full Length Human CHI3L1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: Binding assay
• Molecular Mass: 42.4 kDa
• AA Sequence: MGVKASQTGFVVLVLLQCCSAYKLV CYYTSWSQYREGDGSCFPDALDRFL CTHIIYSFANISNDHIDTWE WNDVTLYGMLNTLKNRNPNLKTLLS VGGWNFGSQRFSKIASNTQSRRTFI KSVPPFLRTHGFDGLDLAWL YPGRRDKQHFTTLIKEMKAEFIKEA QPGKKQLLLSAALSAGKVTIDSSYD IAKISQHLDFISIMTYDFHG AWRGTTGHHSPLFRGQEDASPDRFS NTDYAVGYMLRLGAPASKLVMGIPT FGRSFTLASSETGVGAPISG PGIPGRFTKEAGTLAYYEICDFLRG ATVHRILGQQVPYATKGNQWVGYDD QESVKSKVQYLKDRQLAGAM
  VWALDLDDFQGSFCGQDLRFPLTNA IKDALAATTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein

Gene Information

• Gene Name: CHI3L1 chitinase 3 like 1 [ Homo sapiens (human) ]
• Official Symbol: CHI3L1
• Synonyms: GP39; ASRT7; GP-39; YK-40; YKL40; CGP-39; YKL-40; YYL-40; HC-gp39; HCGP-3P; hCGP-39
• Gene ID: 1116
• mRNA Refseq: NM_001276.4
• Protein Refseq: NP_001267.2
• MIM: 601525
• UniProt ID: P36222