Active Recombinant Full Length Human JMJD6 Protein, C-Flag-tagged

• Cat.No.: JMJD6-301HFL
• Product Overview: Recombinant Full Length Human JMJD6 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: Co-immunoprecipitation
• Molecular Mass: 46.3 kDa
• AA Sequence: MNHKSKKRIREAKRSARPELKDSLD WTRHNYYESFSLSPAAVADNVERAD ALQLSVEEFVERYERPYKPV VLLNAQEGWSAQEKWTLERLKRKYR NQKFKCGEDNDGYSVKMKMKYYIEY MESTRDDSPLYIFDSSYGEH PKRRKLLEDYKVPKFFTDDLFQYAG EKRRPPYRWFVMGPPRSGTGIHIDP LGTSAWNALVQGHKRWCLFP TSTPRELIKVTRDEGGNQQDEAITW FNVIYPRTQLPTWPPEFKPLEILQK PGETVFVPGGWWHVVLNLDT TIAITQNFASSTNFPVVWHKTVRGR PKLSRKWYRILKQEHPELAVLADSV DLQESTGIASDSSSDSSSSS
  SSSSSDSDSECESGSEGDGTVHRRK KRRTCSMVGNGDTTSQDDCVSKERS SSRTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS

Gene Information

• Gene Name: JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase [ Homo sapiens (human) ]
• Official Symbol: JMJD6
• Synonyms: PSR; PTDSR; PTDSR1
• Gene ID: 23210
• mRNA Refseq: NM_015167.3
• Protein Refseq: NP_055982.2
• MIM: 604914
• UniProt ID: Q6NYC1