Active Recombinant Full Length Human MAP2K4 Protein, GST-tagged
Cat.No. : | MAP2K4-5287HF |
Product Overview : | Full-length human MAP2K4 [1-399(end) amino acids of accession number NP_003001.1] was co- expressed as N-terminal GST-fusion protein (71 kDa) with human His-tagged MAP3K3 [1-626(end) amino acids of accession number NP_002392.2] using baculovirus expression system. GST-MAP2K4 was purified by using glutathione sepharose chromatography. |
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Source : | Insect (sf21) |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5 |
Bio-activity : | The activity was determined by ELISA. The enzyme was incubated with GST-fused substrate protein, and after stopping kinase reaction by EDTA, the reaction solution was transferred into glutathione-coated plate. Phosphorylation was detected by anti-phospho antibody and HRP-labeled anti-rabbit IgG(or HRP-labeled anti-mouse IgG) . |
Protein length : | 1-399 |
Purity : | 66% |
Applications : | SDS-PAGE |
Storage : | Store at -80C. Avoid repeating freeze-thaws. |
Gene Name : | mitogen-activated protein kinase kinase 4 |
Official Symbol : | MAP2K4 |
Synonyms : | MAP2K4;JNKK;JNKK1;MAPKK4;MEK4;MKK4;PRKMK4;SAPKK-1;SAPKK1;SEK1;SERK1;SKK1 |
Protein Refseq : | NP_003001.1 |
UniProt ID : | P45985 |
Products Types
◆ Recombinant Protein | ||
MAP2K4-394H | Recombinant Human MAP2K4 Protein, MYC/DDK-tagged | +Inquiry |
MAP2K4-17H | Recombinant Human MAP2K4 Protein, GST-tagged | +Inquiry |
Map2k4-3923M | Recombinant Mouse Map2k4 Protein, Myc/DDK-tagged | +Inquiry |
Map2k4-1351M | Recombinant Mouse Map2k4 protein(Ala2-Asp397), His&GST-tagged | +Inquiry |
MAP2K4-641M | Recombinant Mouse MAP2K4 Protein (2-397 aa), His-SUMO-tagged | +Inquiry |
◆ Lysates | ||
MAP2K4-557MCL | Recombinant Mouse MAP2K4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionTargeting MAP2K4 may provide therapeutic benefits in cancer, modulating cell survival and response to stress.
MAP2K4 helps cells respond to stress, modulating survival and death pathways.
Dysregulation of MAP2K4 has been linked to cancer, affecting cell growth and resistance to apoptosis.
It phosphorylates and activates JNK and p38, transmitting signals in response to stress.
Its activity is regulated by phosphorylation and interaction with other signaling proteins.
MAP2K4 is involved in processes like cell growth, apoptosis, and stress response.
MAP2K4 is a kinase that plays a critical role in activating the JNK and p38 MAPK signaling pathways.
Customer Reviews (3)
Write a reviewGood value, high quality.
Pure product, no issues.
Reliable, worked as described.
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