Active Recombinant Full Length Human RND3 Protein, C-Flag-tagged

• Cat.No.: RND3-541HFL
• Product Overview: Recombinant Full Length Human RND3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: Ex vivo tissue treatment
• Molecular Mass: 27.2 kDa
• AA Sequence: MKERRASQKLSSKSIMDPNQNVKCK IVVVGDSQCGKTALLHVFAKDCFPE NYVPTVFENYTASFEIDTQR IELSLWDTSGSPYYDNVRPLSYPDS DAVLICFDISRPETLDSVLKKWKGE IQEFCPNTKMLLVGCKSDLR TDVSTLVELSNHRQTPVSYDQGANM AKQIGAATYIECSALQSENSVRDIF HVATLACVNKTNKNVKRNKS
  QRATKRISHMPSRPELSAVATDLRK DKAKSCTVMTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: RND3 Rho family GTPase 3 [ Homo sapiens (human) ]
• Official Symbol: RND3
• Synonyms: ARHE; Rho8; RhoE; memB
• Gene ID: 390
• mRNA Refseq: NM_005168.5
• Protein Refseq: NP_005159.1
• MIM: 602924
• UniProt ID: P61587